If you don't have any intention of manipulating clicks, I would say Adsense is definitely the best. Yes, you can't & shouldn't even try manipulating clicks if you're using Adsense because the tracking system is too complicated for you & me to understand. It brings into play all the data from its network - orkut, gmail, adsense, webmaster tools, feedburner, picasa & what not. (So far Adbright is concerned, you can wear your chalta hai attitude).
My experience says:
Adbrite page loading time is higher than that of adsense.
Adsense pays much more than Adbrite. I've received as high as $1.03 dollar for one click (though this happens once in a blue moon). I've noticed that adsense pays less for Indian traffic & higher for US traffic.
Adbrite also sucks because most of the time, your ad space would be blank.
Be it adbrite or adsense, the placement should not disturb your visitors. At the same time, it should be conspicuous enough to fetch you revenue.
On my blog, i use 3 image ads & 1 custom search per page. As of now, I am not using any adlinks except on the search result page.